Their only real argument has been It does not have a USP monograph, which is similar to saying its not FDA approved
GLP-1 drug discovery began with Gila Monster studies, which identified a peptide (extendin-4) in their venom that eventually led to the development of GLP-1 drugs
Aggregation happens when peptide molecules stick together, forming larger complexes that may precipitate from solution or lose biological activity
These medications have been FDA-approved for diabetes management and weight loss
GLP-1 medications work by mimicking the effects of the naturally occurring hormone GLP-1, which plays a vital role in appetite regulation and food intake
Image Credit: Edugrafo / Shutterstock In a recent comprehensive network meta-analysis published in the journal Translational Psychiatry , researchers evaluated the safety and effectiveness of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for individuals with mental illness and comorbid obesity or overweight-related metabolic risk